Ursodeoxycholic acid ameliorates hepatic lipid metabolism in LO2 cells by regulating the AKT/mTOR/SREBP-1 signaling pathway

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD), the most common chronic liver disease, can progress into nonalcoholic steatohepatitis (NASH), cirrhosis, and even hepatocellular carcinoma. Bile acids such as ursodeoxycholic acid (UDCA) play an essential role in the pathogenesis of NAFLD by regu...

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Detaylı Bibliyografya
Yayımlandı:World J Gastroenterol
Asıl Yazarlar: Hu, Jie, Hong, Wei, Yao, Kan-Nan, Zhu, Xiao-Hong, Chen, Zhi-Yun, Ye, Lei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Baishideng Publishing Group Inc 2019
Konular:
Basic Study
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441910/
https://ncbi.nlm.nih.gov/pubmed/30948912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v25.i12.1492
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