TIP30 regulates lipid metabolism in hepatocellular carcinoma by regulating SREBP1 through the Akt/mTOR signaling pathway

Lipid reprogramming has been considered as a crucial characteristic in hepatocellular carcinoma (HCC) initiation and progression. However, detailed molecular mechanisms have yet to be clearly defined. Here, we examined the effects of tumor suppressor TIP30 on the regulation of HCC lipid metabolism....

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Vydáno v:Oncogenesis
Hlavní autoři: Yin, F, Sharen, G, Yuan, F, Peng, Y, Chen, R, Zhou, X, Wei, H, Li, B, Jing, W, Zhao, J
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519197/
https://ncbi.nlm.nih.gov/pubmed/28604762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.49
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