Introduction of the YTE mutation into the non-immunogenic HIV bnAb PGT121 induces anti-drug antibodies in macaques

Recombinant antibodies play increasingly important roles as immunotherapeutic treatments for human cancers as well as inflammatory and infectious diseases and have revolutionized their management. In addition, their therapeutic potential may be enhanced by the introduction of defined mutations in th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Rosenberg, Yvonne J., Lewis, George K., Montefiori, David C., LaBranche, Celia C., Lewis, Mark G., Urban, Lori A., Lees, Jonathan P., Mao, Lingjun, Jiang, Xiaoming
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2019
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437720/
https://ncbi.nlm.nih.gov/pubmed/30785963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0212649
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