Optimization and qualification of a functional anti-drug antibody assay for HIV-1 bnAbs

The recent identification of human monoclonal antibodies with broad and potent neutralizing activity against HIV-1 (bnAbs) has resulted in substantial efforts to develop these molecules for clinical use in the prevention and treatment of HIV-1 infection. As with any protein therapeutic drug product,...

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Publicado no:J Immunol Methods
Main Authors: Seaman, Michael S., Bilska, Miroslawa, Ghantous, Fadi, Eaton, Amanda, LaBranche, Celia C., Greene, Kelli, Gao, Hongmei, Weiner, Joshua A., Ackerman, Margaret E., Garber, David A., Rosenberg, Yvonne J., Sarzotti-Kelsoe, Marcella, Montefiori, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103754/
https://ncbi.nlm.nih.gov/pubmed/31917969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2020.112736
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