Implementation of a three-tiered approach to identify and characterize anti-drug antibodies raised against HIV-specific broadly neutralizing antibodies

The ability to detect, quantify, and interrogate the properties of immune responses raised against biological therapeutics is not only important to our understanding of these molecules, but also to their success in the clinic. A tiered assay approach to identify the presence, specificity, and titer...

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Publicado en:J Immunol Methods
Main Authors: Bharadwaj, Pranay, Riekofski, Cassidy, Lin, Shu, Seaman, Michael S., Garber, David A., Montefiori, David, Sarzotti-Kelsoe, Marcella, Ackerman, Margaret E., Weiner, Joshua A.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103756/
https://ncbi.nlm.nih.gov/pubmed/32070674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2020.112764
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