Implementation of a three-tiered approach to identify and characterize anti-drug antibodies raised against HIV-specific broadly neutralizing antibodies

The ability to detect, quantify, and interrogate the properties of immune responses raised against biological therapeutics is not only important to our understanding of these molecules, but also to their success in the clinic. A tiered assay approach to identify the presence, specificity, and titer...

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Библиографические подробности
Опубликовано в: :J Immunol Methods
Главные авторы: Bharadwaj, Pranay, Riekofski, Cassidy, Lin, Shu, Seaman, Michael S., Garber, David A., Montefiori, David, Sarzotti-Kelsoe, Marcella, Ackerman, Margaret E., Weiner, Joshua A.
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103756/
https://ncbi.nlm.nih.gov/pubmed/32070674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2020.112764
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