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Implementation of a three-tiered approach to identify and characterize anti-drug antibodies raised against HIV-specific broadly neutralizing antibodies

The ability to detect, quantify, and interrogate the properties of immune responses raised against biological therapeutics is not only important to our understanding of these molecules, but also to their success in the clinic. A tiered assay approach to identify the presence, specificity, and titer...

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Bibliografiska uppgifter
I publikationen:J Immunol Methods
Huvudupphovsmän: Bharadwaj, Pranay, Riekofski, Cassidy, Lin, Shu, Seaman, Michael S., Garber, David A., Montefiori, David, Sarzotti-Kelsoe, Marcella, Ackerman, Margaret E., Weiner, Joshua A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103756/
https://ncbi.nlm.nih.gov/pubmed/32070674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2020.112764
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