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An Aminoimidazole Radical Intermediate in the Anaerobic Biosynthesis of the 5,6-dimethylbenzimidazole Ligand to Vitamin B12

Organisms that perform the de novo biosynthesis of cobalamin (vitamin B12) do so via unique pathways depending on the presence of oxygen in the environment. The anaerobic biosynthesis pathway of 5,6-dimethylbenzimidazole, the so-called “lower ligand” to the cobalt center, has been recently identifie...

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Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Gagnon, Derek M., Stich, Troy A., Mehta, Angad P., Abdelwahed, Sameh H., Begley, Tadhg P., Britt, R. David
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435355/
https://ncbi.nlm.nih.gov/pubmed/30208703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b05686
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