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An Aminoimidazole Radical Intermediate in the Anaerobic Biosynthesis of the 5,6-dimethylbenzimidazole Ligand to Vitamin B12

Organisms that perform the de novo biosynthesis of cobalamin (vitamin B12) do so via unique pathways depending on the presence of oxygen in the environment. The anaerobic biosynthesis pathway of 5,6-dimethylbenzimidazole, the so-called “lower ligand” to the cobalt center, has been recently identifie...

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Detalles Bibliográficos
Publicado en:J Am Chem Soc
Main Authors: Gagnon, Derek M., Stich, Troy A., Mehta, Angad P., Abdelwahed, Sameh H., Begley, Tadhg P., Britt, R. David
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6435355/
https://ncbi.nlm.nih.gov/pubmed/30208703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b05686
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