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Molybdopterin biosynthesis: Trapping an unusual purine ribose adduct in the MoaA-catalyzed reaction

MoaA/MoaC catalyze a remarkable rearrangement reaction in which guanosine-5′-triphosphate (GTP) is converted to cyclicpyranopterin monophosphate (cPMP). In this reaction, the C8 of GTP is inserted between the C2′ and the C3′ carbons of the GTP ribose. Previous experiments with GTP isotopomers demons...

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書誌詳細
主要な著者: Mehta, Angad P., Abdelwahed, Sameh H., Begley, Tadhg P.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804160/
https://ncbi.nlm.nih.gov/pubmed/23848839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4041048
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