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Catalysis of a new ribose carbon–insertion reaction by the molybdenum cofactor biosynthetic enzyme MoaA
MoaA, a radical S-adenosylmethionine (SAM) enzyme, catalyzes the first step in molybdopterin biosynthesis. This reaction involves a complex rearrangement in which C8 of guanosine triphosphtate is inserted between the C2′ and the C3′ carbons of the ribose. This study identifies the site of initial hy...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3582411/ https://ncbi.nlm.nih.gov/pubmed/23286307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3016026 |
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