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Type 2 diabetes is associated with suppression of autophagy and lipid accumulation in β‐cells

Both type 2 diabetes (T2D) and obesity are characterized by excessive hyperlipidaemia and subsequent lipid droplet (LD) accumulation in adipose tissue. To investigate whether LDs also accumulate in β‐cells of T2D patients, we assessed the expression of PLIN2, a LD‐associated protein, in non‐diabetic...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Cell Mol Med
Asıl Yazarlar: Ji, Jeff, Petropavlovskaia, Maria, Khatchadourian, Armen, Patapas, Jason, Makhlin, Julia, Rosenberg, Lawrence, Maysinger, Dusica
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433726/
https://ncbi.nlm.nih.gov/pubmed/30710421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14172
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