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Type 2 diabetes is associated with suppression of autophagy and lipid accumulation in β‐cells

Both type 2 diabetes (T2D) and obesity are characterized by excessive hyperlipidaemia and subsequent lipid droplet (LD) accumulation in adipose tissue. To investigate whether LDs also accumulate in β‐cells of T2D patients, we assessed the expression of PLIN2, a LD‐associated protein, in non‐diabetic...

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Dades bibliogràfiques
Publicat a:J Cell Mol Med
Autors principals: Ji, Jeff, Petropavlovskaia, Maria, Khatchadourian, Armen, Patapas, Jason, Makhlin, Julia, Rosenberg, Lawrence, Maysinger, Dusica
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433726/
https://ncbi.nlm.nih.gov/pubmed/30710421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14172
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