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Islet neogenesis associated protein (INGAP) protects pancreatic β cells from IL-1β and IFNγ-induced apoptosis

The goal of this study was to determine whether recombinant Islet NeoGenesis Associated Protein (rINGAP) and its active core, a pentadecapeptide INGAP(104–118) (Ingap-p), protect β cells against cytokine-induced death. INGAP has been shown to induce islet neogenesis in diabetic animals, to stimulate...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Nano, Eni, Petropavlovskaia, Maria, Rosenberg, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969959/
https://ncbi.nlm.nih.gov/pubmed/33731692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00441-z
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