Cloning and sequencing of the pancreatic islet neogenesis associated protein (INGAP) gene and its expression in islet neogenesis in hamsters.

Induction of islet neogenesis by cellophane wrapping (CW) reverses streptozotocin-induced (STZ) diabetes. Administration of Ilotropin, a protein extract isolated from CW pancreata, causes recapitulation of normal islet ontogeny and reverses STZ diabetes, reducing mortality by 50%. We investigated th...

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Detalhes bibliográficos
Main Authors: Rafaeloff, R., Pittenger, G. L., Barlow, S. W., Qin, X. F., Yan, B., Rosenberg, L., Duguid, W. P., Vinik, A. I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC508040/
https://ncbi.nlm.nih.gov/pubmed/9151782
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