A Pentadecapeptide Fragment of Islet Neogenesis-Associated Protein Increases Beta-Cell Mass and Reverses Diabetes in C57BL/6J Mice

OBJECTIVE: The objective of this study was to demonstrate that islet neogenesis-associated protein (INGAP) peptide, a pentadecapeptide containing the biologically active portion of native INGAP, increases functional β-cell mass in normal animals and can be used therapeutically to reverse hyperglycem...

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Detalhes bibliográficos
Main Authors: Rosenberg, Lawrence, Lipsett, Mark, Yoon, Ji-Won, Prentki, Marc, Wang, Rennian, Jun, Hee-Sook, Pittenger, Gary L., Taylor-Fishwick, David, Vinik, Aaron I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356495/
https://ncbi.nlm.nih.gov/pubmed/15492571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.sla.0000143270.99191.10
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