Islet Neogenesis: A Possible Pathway for Beta-Cell Replenishment

Diabetes, particularly type 1 diabetes, results from the lack of pancreatic β-cells. β-cell replenishment can functionally reverse diabetes, but two critical challenges face the field: 1. protection of the new β-cells from autoimmunity and allorejection, and 2. development of β-cells that are readil...

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Main Authors: Bonner-Weir, Susan, Guo, Lili, Li, Wan-Chun, Ouziel-Yahalom, Limor, Lysy, Philippe A., Weir, Gordon C., Sharma, Arun
Format: Artigo
Jezik:Inglês
Izdano: SBDR - Society for Biomedical Diabetes Research 2012
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740706/
https://ncbi.nlm.nih.gov/pubmed/23804276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2012.9.407
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