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Defective insulin secretory response to intravenous glucose in C57Bl/6J compared to C57Bl/6N mice
OBJECTIVE: The C57Bl/6J (Bl/6J) mouse is the most widely used strain in metabolic research. This strain carries a mutation in nicotinamide nucleotide transhydrogenase (Nnt), a mitochondrial enzyme involved in NADPH production, which has been suggested to lead to glucose intolerance and beta-cell dys...
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Publicado no: | Mol Metab |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4264561/ https://ncbi.nlm.nih.gov/pubmed/25506550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2014.09.006 |
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