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β-Hydroxybutyrate Suppresses Lipid Accumulation in Aged Liver through GPR109A-mediated Signaling

Dietary interventions such as prolonged calorie restriction (CR) and intermittent fasting provide health benefits including a reduction in the inflammatory burden and regulation of energy metabolism. During CR, β-hydroxybutyrate (BHB) level is elevated in the serum. BHB is a ligand of GPR109A, which...

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Detalhes bibliográficos
Publicado no:Aging Dis
Main Authors: Lee, A Kyoung, Kim, Dae Hyun, Bang, EunJin, Choi, Yeon Ja, Chung, Hae Young
Formato: Artigo
Idioma:Inglês
Publicado em: JKL International LLC 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390524/
https://ncbi.nlm.nih.gov/pubmed/32765945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2019.0926
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