Interaction between CHOP and FoxO6 promotes hepatic lipid accumulation

BACKGROUND & AIMS: Endoplasmic reticulum (ER) stress is one of the major causes of hepatic insulin resistance through increasing de novo lipogenesis. Forkhead box O6 (FoxO6) is a transcription factor mediating insulin signalling to glucose and lipid metabolism, therefore, dysregulated FoxO6 is i...

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Bibliografiske detaljer
Udgivet i:Liver Int
Main Authors: Kim, Dae Hyun, Kim, Byeong Moo, Chung, Ki Wung, Choi, Yeon Ja, Yu, Byung Pal, Chung, Hae Young
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Metabolic & Toxic Liver Diseases
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689817/
https://ncbi.nlm.nih.gov/pubmed/32639626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.14594
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