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Type 2 diabetes is associated with suppression of autophagy and lipid accumulation in β‐cells

Both type 2 diabetes (T2D) and obesity are characterized by excessive hyperlipidaemia and subsequent lipid droplet (LD) accumulation in adipose tissue. To investigate whether LDs also accumulate in β‐cells of T2D patients, we assessed the expression of PLIN2, a LD‐associated protein, in non‐diabetic...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Ji, Jeff, Petropavlovskaia, Maria, Khatchadourian, Armen, Patapas, Jason, Makhlin, Julia, Rosenberg, Lawrence, Maysinger, Dusica
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433726/
https://ncbi.nlm.nih.gov/pubmed/30710421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14172
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