DNA elements for constitutive androstane receptor- and pregnane X receptor-mediated regulation of bovine CYP3A28 gene

The regulation of cytochrome P450 3A (CYP3A) enzymes is established in humans, but molecular mechanisms of its basal and xenobiotic-mediated regulation in cattle are still unknown. Here, ~10 kbp of the bovine CYP3A28 gene promoter were cloned and sequenced, and putative transcription factor binding...

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Vydáno v:PLoS One
Hlavní autoři: Giantin, Mery, Küblbeck, Jenni, Zancanella, Vanessa, Prantner, Viktoria, Sansonetti, Fabiana, Schoeniger, Axel, Tolosi, Roberta, Guerra, Giorgia, Da Ros, Silvia, Dacasto, Mauro, Honkakoski, Paavo
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433341/
https://ncbi.nlm.nih.gov/pubmed/30908543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214338
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