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Metabolism-Disrupting Chemicals and the Constitutive Androstane Receptor CAR

During the last two decades, the constitutive androstane receptor (CAR; NR1I3) has emerged as a master activator of drug- and xenobiotic-metabolizing enzymes and transporters that govern the clearance of both exogenous and endogenous small molecules. Recent studies indicate that CAR participates, to...

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Bibliografske podrobnosti
Main Authors: Jenni Küblbeck, Jonna Niskanen, Paavo Honkakoski
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2020-10-01
Serija:Cells
Teme:
Online dostop:https://www.mdpi.com/2073-4409/9/10/2306
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