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Metabolism-Disrupting Chemicals and the Constitutive Androstane Receptor CAR
During the last two decades, the constitutive androstane receptor (CAR; NR1I3) has emerged as a master activator of drug- and xenobiotic-metabolizing enzymes and transporters that govern the clearance of both exogenous and endogenous small molecules. Recent studies indicate that CAR participates, to...
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Main Authors: | , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
MDPI AG
2020-10-01
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Serija: | Cells |
Teme: | |
Online dostop: | https://www.mdpi.com/2073-4409/9/10/2306 |
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