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Signaling control of the constitutive androstane receptor (CAR)
The constitutive androstane receptor (CAR, NR1I3) plays a crucial role in the regulation of drug metabolism, energy homeostasis, and cancer development through modulating the transcription of its numerous target genes. Different from prototypical nuclear receptors, CAR can be activated by either dir...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Higher Education Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3956974/ https://ncbi.nlm.nih.gov/pubmed/24474196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-013-0013-0 |
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