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Signaling control of the constitutive androstane receptor (CAR)
The constitutive androstane receptor (CAR, NR1I3) plays a crucial role in the regulation of drug metabolism, energy homeostasis, and cancer development through modulating the transcription of its numerous target genes. Different from prototypical nuclear receptors, CAR can be activated by either dir...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Higher Education Press
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3956974/ https://ncbi.nlm.nih.gov/pubmed/24474196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-013-0013-0 |
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