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Metabolism-Disrupting Chemicals and the Constitutive Androstane Receptor CAR

During the last two decades, the constitutive androstane receptor (CAR; NR1I3) has emerged as a master activator of drug- and xenobiotic-metabolizing enzymes and transporters that govern the clearance of both exogenous and endogenous small molecules. Recent studies indicate that CAR participates, to...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Küblbeck, Jenni, Niskanen, Jonna, Honkakoski, Paavo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7602645/
https://ncbi.nlm.nih.gov/pubmed/33076503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102306
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