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Metabolism-Disrupting Chemicals and the Constitutive Androstane Receptor CAR
During the last two decades, the constitutive androstane receptor (CAR; NR1I3) has emerged as a master activator of drug- and xenobiotic-metabolizing enzymes and transporters that govern the clearance of both exogenous and endogenous small molecules. Recent studies indicate that CAR participates, to...
Guardat en:
| Publicat a: | Cells |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7602645/ https://ncbi.nlm.nih.gov/pubmed/33076503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102306 |
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