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Dual action of oestrogens on the mouse constitutive androstane receptor.
mCAR (mouse constitutive androstane receptor; NR1I3) controls the expression of cytochrome P450 as well as other enzymes involved in drug and steroid metabolism. The high basal activity of mCAR can be modulated by inhibitory steroids related to androstenol and by activating xenobiotic chemicals such...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223782/ https://ncbi.nlm.nih.gov/pubmed/12948398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030553 |
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