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The constitutive androstane receptor and pregnane X receptor in the brain
Since their discovery, the orphan nuclear receptors constitutive androstane receptor (CAR;NR1I3) and pregnane X receptor (PXR;NR1I2) have been regarded as master regulators of drug disposition and detoxification mechanisms. They regulate the metabolism and transport of endogenous mediators and xenob...
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| Udgivet i: | Br J Pharmacol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7236070/ https://ncbi.nlm.nih.gov/pubmed/32201941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15055 |
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