Functional impact of cytochrome P450 3A (CYP3A) missense variants in cattle

Cytochrome P450 3A is the most important CYP subfamily in humans, and CYP3A4/CYP3A5 genetic variants contribute to inter-individual variability in drug metabolism. However, no information is available for bovine CYP3A (bCYP3A). Here we described bCYP3A missense single nucleotide variants (SNVs) and...

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Foilsithe in:Sci Rep
Main Authors: Giantin, Mery, Rahnasto-Rilla, Minna, Tolosi, Roberta, Lucatello, Lorena, Pauletto, Marianna, Guerra, Giorgia, Pezzato, Francesca, Lopparelli, Rosa M., Merlanti, Roberta, Carnier, Paolo, Capolongo, Francesca, Honkakoski, Paavo, Dacasto, Mauro
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2019
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6927969/
https://ncbi.nlm.nih.gov/pubmed/31873175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56271-8
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