PrP-grafted antibodies bind certain amyloid β-protein aggregates, but do not prevent toxicity

BACKGROUND: The prion protein (PrP) is known to bind certain soluble aggregates of the amyloid β-protein (Aβ), and two regions of PrP, one centered around residues 19–33, and the other around 87–112, are thought to be particularly important for this interaction. When either of these sequences are gr...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Brain Res
Main Authors: Mengel, David, Hong, Wei, Corbett, Grant T., Liu, Wen, DeSousa, Alexandra, Solforosi, Laura, Fang, Cheng, Frosch, Matthew P., Collinge, John, Harris, David, Walsh, Dominic M.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6431553/
https://ncbi.nlm.nih.gov/pubmed/30593771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2018.12.038
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker