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Reversible histone glycation is associated with disease-related changes in chromatin architecture
Cellular proteins continuously undergo non-enzymatic covalent modifications (NECMs) that accumulate under normal physiological conditions and are stimulated by changes in the cellular microenvironment. Glycation, the hallmark of diabetes, is a prevalent NECM associated with an array of pathologies....
Kaydedildi:
| Yayımlandı: | Nat Commun |
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| Asıl Yazarlar: | , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group UK
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6426841/ https://ncbi.nlm.nih.gov/pubmed/30894531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09192-z |
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