H1 histones control the epigenetic landscape by local chromatin compaction

H1 linker histones are the most abundant chromatin-binding proteins(1). In vitro studies indicate that their association with chromatin determines nucleosome spacing and enables arrays of nucleosomes to fold into more compact chromatin structures. However, the in vivo roles of H1 are poorly understo...

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Udgivet i:Nature
Main Authors: Willcockson, Michael A., Healton, Sean E., Weiss, Cary N., Bartholdy, Boris A., Botbol, Yair, Mishra, Laxmi N., Sidhwani, Dhruv S., Wilson, Tommy J., Pinto, Hugo B., Maron, Maxim I., Skalina, Karin A., Toro, Laura Norwood, Zhao, Jie, Lee, Chul-Hwan, Hou, Harry, Yusufova, Nevin, Meydan, Cem, Osunsade, Adewola, David, Yael, Cesarman, Ethel, Melnick, Ari M., Sidoli, Simone, Garcia, Benjamin A., Edelmann, Winfried, Macian, Fernando, Skoultchi, Arthur I.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8110206/
https://ncbi.nlm.nih.gov/pubmed/33299182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-3032-z
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