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Controlling the viscosities of antibody solutions through control of their binding sites

For biotechnological drugs, it is desirable to formulate antibody solutions with low viscosities. We go beyond previous colloid theories in treating protein–protein self–association of molecules that are antibody–shaped and flexible and have spatially specific binding sites. We consider interactions...

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Bibliografische gegevens
Gepubliceerd in:J Mol Liq
Hoofdauteurs: Kastelic, Miha, Dill, Ken A., Kalyuzhnyi, Yura V., Vlachy, Vojko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425977/
https://ncbi.nlm.nih.gov/pubmed/30906093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molliq.2017.11.106
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