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Theory for the Liquid–Liquid Phase Separation in Aqueous Antibody Solutions

This study presents the theory for liquid–liquid phase separation for systems of molecules modeling monoclonal antibodies. Individual molecule is depicted as an assembly of seven hard spheres, organized to mimic the Y-shaped antibody. We consider the antibody–antibody interactions either through Fab...

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Detalles Bibliográficos
Publicado en:J Phys Chem B
Main Authors: Kastelic, Miha, Vlachy, Vojko
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980754/
https://ncbi.nlm.nih.gov/pubmed/29338267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.7b11458
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