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Controlling the viscosities of antibody solutions through control of their binding sites

For biotechnological drugs, it is desirable to formulate antibody solutions with low viscosities. We go beyond previous colloid theories in treating protein–protein self–association of molecules that are antibody–shaped and flexible and have spatially specific binding sites. We consider interactions...

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Dades bibliogràfiques
Publicat a:J Mol Liq
Autors principals: Kastelic, Miha, Dill, Ken A., Kalyuzhnyi, Yura V., Vlachy, Vojko
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425977/
https://ncbi.nlm.nih.gov/pubmed/30906093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molliq.2017.11.106
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