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Controlling the viscosities of antibody solutions through control of their binding sites

For biotechnological drugs, it is desirable to formulate antibody solutions with low viscosities. We go beyond previous colloid theories in treating protein–protein self–association of molecules that are antibody–shaped and flexible and have spatially specific binding sites. We consider interactions...

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Detalhes bibliográficos
Publicado no:J Mol Liq
Main Authors: Kastelic, Miha, Dill, Ken A., Kalyuzhnyi, Yura V., Vlachy, Vojko
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6425977/
https://ncbi.nlm.nih.gov/pubmed/30906093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molliq.2017.11.106
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