Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation

Cellular functions of arrestins are determined in part by the pattern of phosphorylation on the G protein-coupled receptors (GPCRs) to which arrestins bind. Despite high-resolution structural data of arrestins bound to phosphorylated receptor C-termini, the functional role of each phosphorylation si...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Mayer, Daniel, Damberger, Fred F., Samarasimhareddy, Mamidi, Feldmueller, Miki, Vuckovic, Ziva, Flock, Tilman, Bauer, Brian, Mutt, Eshita, Zosel, Franziska, Allain, Frédéric H. T., Standfuss, Jörg, Schertler, Gebhard F. X., Deupi, Xavier, Sommer, Martha E., Hurevich, Mattan, Friedler, Assaf, Veprintsev, Dmitry B.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424980/
https://ncbi.nlm.nih.gov/pubmed/30890705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09204-y
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker