טוען...
Functional map of arrestin-1 at single amino acid resolution
Arrestins function as adapter proteins that mediate G protein-coupled receptor (GPCR) desensitization, internalization, and additional rounds of signaling. Here we have compared binding of the GPCR rhodopsin to 403 mutants of arrestin-1 covering its complete sequence. This comprehensive and unbiased...
שמור ב:
| Main Authors: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3918777/ https://ncbi.nlm.nih.gov/pubmed/24449856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319402111 |
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