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Roles of the ClpX IGF loops in ClpP association, dissociation, and protein degradation

IGF‐motif loops project from the hexameric ring of ClpX and are required for docking with the self‐compartmentalized ClpP peptidase, which consists of heptameric rings stacked back‐to‐back. Here, we show that ATP or ATPγS support assembly by changing the conformation of the ClpX ring, bringing the I...

詳細記述

保存先:
書誌詳細
出版年:Protein Sci
主要な著者: Amor, Alvaro J., Schmitz, Karl R., Baker, Tania A., Sauer, Robert T.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley & Sons, Inc. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423715/
https://ncbi.nlm.nih.gov/pubmed/30767302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3590
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