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Roles of the ClpX IGF loops in ClpP association, dissociation, and protein degradation
IGF‐motif loops project from the hexameric ring of ClpX and are required for docking with the self‐compartmentalized ClpP peptidase, which consists of heptameric rings stacked back‐to‐back. Here, we show that ATP or ATPγS support assembly by changing the conformation of the ClpX ring, bringing the I...
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| Publicado en: | Protein Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley & Sons, Inc.
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6423715/ https://ncbi.nlm.nih.gov/pubmed/30767302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3590 |
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