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Roles of the ClpX IGF loops in ClpP association, dissociation, and protein degradation

IGF‐motif loops project from the hexameric ring of ClpX and are required for docking with the self‐compartmentalized ClpP peptidase, which consists of heptameric rings stacked back‐to‐back. Here, we show that ATP or ATPγS support assembly by changing the conformation of the ClpX ring, bringing the I...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Protein Sci
Egile Nagusiak: Amor, Alvaro J., Schmitz, Karl R., Baker, Tania A., Sauer, Robert T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley & Sons, Inc. 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423715/
https://ncbi.nlm.nih.gov/pubmed/30767302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3590
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