The polyadenylation inhibitor cordycepin reduces pain, inflammation and joint pathology in rodent models of osteoarthritis

Clinically, osteoarthritis (OA) pain is significantly associated with synovial inflammation. Identification of the mechanisms driving inflammation could reveal new targets to relieve this prevalent pain state. Herein, a role of polyadenylation in OA synovial samples was investigated, and the potenti...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Ashraf, Sadaf, Radhi, Masar, Gowler, Peter, Burston, James J., Gandhi, Raj D., Thorn, Graeme J., Piccinini, Anna M., Walsh, David A., Chapman, Victoria, de Moor, Cornelia H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423048/
https://ncbi.nlm.nih.gov/pubmed/30886197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41140-1
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