A novel nucleoside rescue metabolic pathway may be responsible for therapeutic effect of orally administered cordycepin

Although adenosine and its analogues have been assessed in the past as potential drug candidates due to the important role of adenosine in physiology, only little is known about their absorption following oral administration. In this work, we have studied the oral absorption and disposition pathways...

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Publicado en:Sci Rep
Autores principales: Lee, Jong Bong, Radhi, Masar, Cipolla, Elena, Gandhi, Raj D., Sarmad, Sarir, Zgair, Atheer, Kim, Tae Hwan, Feng, Wanshan, Qin, Chaolong, Adrower, Cecilia, Ortori, Catherine A., Barrett, David A., Kagan, Leonid, Fischer, Peter M., de Moor, Cornelia H., Gershkovich, Pavel
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6823370/
https://ncbi.nlm.nih.gov/pubmed/31673018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52254-x
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