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A novel nucleoside rescue metabolic pathway may be responsible for therapeutic effect of orally administered cordycepin

Although adenosine and its analogues have been assessed in the past as potential drug candidates due to the important role of adenosine in physiology, only little is known about their absorption following oral administration. In this work, we have studied the oral absorption and disposition pathways...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Lee, Jong Bong, Radhi, Masar, Cipolla, Elena, Gandhi, Raj D., Sarmad, Sarir, Zgair, Atheer, Kim, Tae Hwan, Feng, Wanshan, Qin, Chaolong, Adrower, Cecilia, Ortori, Catherine A., Barrett, David A., Kagan, Leonid, Fischer, Peter M., de Moor, Cornelia H., Gershkovich, Pavel
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6823370/
https://ncbi.nlm.nih.gov/pubmed/31673018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52254-x
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