A novel nucleoside rescue metabolic pathway may be responsible for therapeutic effect of orally administered cordycepin

Although adenosine and its analogues have been assessed in the past as potential drug candidates due to the important role of adenosine in physiology, only little is known about their absorption following oral administration. In this work, we have studied the oral absorption and disposition pathways...

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Publicat a:Sci Rep
Autors principals: Lee, Jong Bong, Radhi, Masar, Cipolla, Elena, Gandhi, Raj D., Sarmad, Sarir, Zgair, Atheer, Kim, Tae Hwan, Feng, Wanshan, Qin, Chaolong, Adrower, Cecilia, Ortori, Catherine A., Barrett, David A., Kagan, Leonid, Fischer, Peter M., de Moor, Cornelia H., Gershkovich, Pavel
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6823370/
https://ncbi.nlm.nih.gov/pubmed/31673018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52254-x
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