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Refining surgical models of osteoarthritis in mice and rats alters pain phenotype but not joint pathology

The relationship between osteoarthritis (OA) structural change and pain is complex. Surgical models of OA in rodents are often rapid in onset, limiting mechanistic utility and translational validity. We aimed to investigate the effect of refining surgical small rodent models of OA on both joint path...

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發表在:PLoS One
Main Authors: Gowler, Peter R. W., Mapp, Paul I., Burston, James J., Shahtaheri, Mohsen, Walsh, David A., Chapman, Victoria
格式: Artigo
語言:Inglês
出版: Public Library of Science 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523978/
https://ncbi.nlm.nih.gov/pubmed/32991618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239663
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