Differences in structural and pain phenotypes in the sodium monoiodoacetate and meniscal transection models of osteoarthritis

OBJECTIVES: To characterize differences in joint pathology and pain behavior between two rat models of osteoarthritis (OA) in order to inform selection of animal models for interventional studies. METHOD: Knee OA was induced in Sprague Dawley rats by either meniscal transection (MNX) or intra-articu...

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Main Authors: Mapp, P.I., Sagar, D.R., Ashraf, S., Burston, J.J., Suri, S., Chapman, V., Walsh, D.A.
Format: Artigo
Sprog:Inglês
Udgivet: W.B. Saunders For The Osteoarthritis Research Society 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790974/
https://ncbi.nlm.nih.gov/pubmed/23973148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2013.06.031
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