Refining surgical models of osteoarthritis in mice and rats alters pain phenotype but not joint pathology

The relationship between osteoarthritis (OA) structural change and pain is complex. Surgical models of OA in rodents are often rapid in onset, limiting mechanistic utility and translational validity. We aimed to investigate the effect of refining surgical small rodent models of OA on both joint path...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Gowler, Peter R. W., Mapp, Paul I., Burston, James J., Shahtaheri, Mohsen, Walsh, David A., Chapman, Victoria
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523978/
https://ncbi.nlm.nih.gov/pubmed/32991618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239663
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