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Targeted Single Primer Enrichment Sequencing with Single End Duplex-UMI
For specific detection of somatic variants at very low levels, artifacts from the NGS workflow have to be eliminated. Various approaches using unique molecular identifiers (UMI) to analytically remove NGS artifacts have been described. Among them, Duplex-seq was shown to be highly effective, by leve...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6423013/ https://ncbi.nlm.nih.gov/pubmed/30886209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41215-z |
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