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Targeted Single Primer Enrichment Sequencing with Single End Duplex-UMI

For specific detection of somatic variants at very low levels, artifacts from the NGS workflow have to be eliminated. Various approaches using unique molecular identifiers (UMI) to analytically remove NGS artifacts have been described. Among them, Duplex-seq was shown to be highly effective, by leve...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Peng, Quan, Xu, Chang, Kim, Daniel, Lewis, Marcus, DiCarlo, John, Wang, Yexun
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423013/
https://ncbi.nlm.nih.gov/pubmed/30886209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41215-z
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