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Discovery of a novel DNA polymerase inhibitor and characterization of its antiproliferative properties
Chromosomal duplication is targeted by various chemotherapeutic agents for the treatment of cancer. However, there is no specific inhibitor of DNA polymerases that is viable for cancer management. Through structure-based in silico screening of the ZINC database, we identified a specific inhibitor of...
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| Publicado no: | Cancer Biol Ther |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6422523/ https://ncbi.nlm.nih.gov/pubmed/30427259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2018.1529126 |
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