Expression of the p12 subunit of human DNA polymerase δ (Pol δ), CDK inhibitor p21(WAF1), Cdt1, cyclin A, PCNA and Ki-67 in relation to DNA replication in individual cells

We recently reported that the p12 subunit of human DNA polymerase δ (Pol δ4) is degraded by CRL4(Cdt2) which regulates the licensing factor Cdt1 and p21(WAF1) during the G(1) to S transition. Presently, we performed multiparameter laser scanning cytometric analyses of changes in levels of p12, Cdt1...

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Vydáno v:Cell Cycle
Hlavní autoři: Zhao, Hong, Zhang, Sufang, Xu, Dazhong, Lee, Marietta YWT, Zhang, Zhongtao, Lee, Ernest YC, Darzynkiewicz, Zbigniew
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614631/
https://ncbi.nlm.nih.gov/pubmed/25483089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.958910
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