Phosphorylation Alters the Properties of Pol η: Implications for Translesion Synthesis

There are significant ambiguities regarding how DNA polymerase η is recruited to DNA lesion sites in stressed cells while avoiding normal replication forks in non-stressed cells. Even less is known about the mechanisms responsible for Pol η-induced mutations in cancer genomes. We show that there are...

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Publicado no:iScience
Main Authors: Peddu, Chandana, Zhang, Sufang, Zhao, Hong, Wong, Agnes, Lee, Ernest Y.C., Lee, Marietta Y.W.T., Zhang, Zhongtao
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137289/
https://ncbi.nlm.nih.gov/pubmed/30240625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.07.009
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