Structure of monoubiquitinated PCNA: Implications for DNA polymerase switching and Okazaki fragment maturation

Ubiquitination of proliferating cell nuclear antigen (PCNA) to ub-PCNA is essential for DNA replication across bulky template lesions caused by UV radiation and alkylating agents, as ub-PCNA orchestrates the recruitment and switching of translesion synthesis (TLS) polymerases with replication polyme...

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Detalhes bibliográficos
Main Authors: Zhang, Zhongtao, Zhang, Sufang, Lin, Szu Hua Sharon, Wang, Xiaoxiao, Wu, Licheng, Lee, Ernest Y.C., Lee, Marietta Y.W.T.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368864/
https://ncbi.nlm.nih.gov/pubmed/22592530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.20595
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