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Structure of monoubiquitinated PCNA: Implications for DNA polymerase switching and Okazaki fragment maturation
Ubiquitination of proliferating cell nuclear antigen (PCNA) to ub-PCNA is essential for DNA replication across bulky template lesions caused by UV radiation and alkylating agents, as ub-PCNA orchestrates the recruitment and switching of translesion synthesis (TLS) polymerases with replication polyme...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Landes Bioscience
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368864/ https://ncbi.nlm.nih.gov/pubmed/22592530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.20595 |
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